Common genetic variation in gene may modify cardiovascular benefit of aspirin
Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease.
View ArticleUnnatural DNA bases: an interview with Professor Floyd E. Romesberg, The...
The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their...
View ArticleCo-targeting strategies suggested for EGFR-TKI resistance in NSCLC
Researchers have identified additional resistance mechanisms that could be targeted to improve the efficacy of irreversible epidermal growth factor receptor-tyrosine kinase inhibitors in patients with...
View ArticleEpidurals and reduced postpartum depression: an interview with Dr. Zakowski
The “maternity blues”, which resolve within 10 days of giving birth, occurs in up to 80% of new moms. A major depressive episode, by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)...
View ArticleLeading academics underscore the importance of diet and nutrition for mental...
Evidence is rapidly growing showing vital relationships between both diet quality and potential nutritional deficiencies and mental health, a new international collaboration led by the University of...
View ArticleMSU scientists identify antioxidant system that backs up liver during crisis
Scientists from Montana State University and Sweden have discovered an antioxidant system that helps sustain the liver when other systems are missing or compromised.
View ArticleMSI completes patient recruitment for STRADA Phase 2 trial for treatment of...
MSI Methylation Sciences, Inc., a pharmaceutical company developing a once-daily oral, small molecule therapy for adjunctive treatment of major depressive disorder (MDD), announced the completion of...
View ArticleNew UAB research identifies link between temporal lobe epilepsy and memory loss
New research from the University of Alabama at Birmingham identifies an epigenetic cause for why patients with temporal lobe epilepsy tend to have memory loss, and suggests a potential way to reverse...
View ArticleStudy examines how low-methionine diet may help improve outcomes in...
A diet that starves triple-negative breast cancer cells of an essential nutrient primes the cancer cells to be more easily killed by a targeted antibody treatment, UW Carbone Cancer Center scientists...
View Article‘Medical foods’ for patients with rare IEMs may cause harm when not carefully...
Many "medical foods" are designed to help manage patients with rare inborn errors of metabolism (IEMs), and can help prevent serious and life-threatening complications. However, such special foods may...
View ArticleHelmholtz Centre for Infection Research scientists identify promising...
Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of...
View ArticleChanges in cellular metabolites regulate earliest stages of embryonic stem...
Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical...
View ArticleStructural movie reveals step-by-step creation of chemical that plays...
An international team of scientists led by the University of Liverpool has produced a 'structural movie' revealing the step-by-step creation of an important naturally occurring chemical in the body...
View ArticleFood-based proteins can help address child malnutrition in developing countries
Contrary to popular belief among world relief workers, children in developing countries may not be eating enough protein, which could contribute to stunted growth, a Johns Hopkins-directed study suggests.
View ArticleHealthy cells actively collaborate with tumours to promote growth of new...
Healthy cells actively collaborate with tumours by creating a mesh of collagen that encourages cancer cells to build new blood vessels, a new study shows.
View ArticleAbsence of PEMT enzyme leads to development of fatty liver disease and...
Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.
View ArticleAltered metabolism of two essential amino acids helps drive development of...
The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State...
View ArticleNanoparticle-based gene therapy may hold promise for patients with asthma
A new study has demonstrated a way to deliver a nanoparticle-based gene therapy, in order to repair lungs damaged by chronic allergic asthma and to reduce inflammation that causes asthma attacks.
View ArticleRare antibiotic compound detected in fungi for first time
Besides mushrooms such as truffles or morels, also many yeast and mould fungi, as well as other filamentous fungi belong to the Ascomycota phylum. They produce metabolic products which can act as...
View ArticleUAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia
Though the drug levodopa can dramatically improve Parkinson's disease symptoms, within five years one-half of the patients using L-DOPA develop an irreversible condition -- involuntary repetitive,...
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